Solcoseryl dental adhesive paste for topical use, 5 g

pharmachologic effect

Combined preparation for local use, stimulator of tissue regeneration.

The drug is a chemically and biologically standardized deproteinized dialysate obtained from the blood of healthy dairy calves using the ultrafiltration method. Contains a wide range of natural low-molecular compounds weighing up to 5000 Daltons: glycolipids, nucleosides and nucleotides, amino acids, oligopeptides, trace elements, electrolytes, intermediate products of carbohydrate and fat metabolism. Activates the transport of oxygen and nutrients at the cellular level, increases oxygen consumption by the cell, stimulates ATP synthesis, enhances the proliferation of reversibly damaged cells, especially under hypoxic conditions, thereby accelerating wound healing processes. Stimulates angiogenesis, promotes revascularization of ischemic tissue, as well as creating conditions favorable for collagen synthesis and the growth of fresh granulation tissue, accelerates re-epithelialization and wound closure. The drug also has membrane-stabilizing and cytoprotective effects.

Polidocanol 600 - local anesthetic; acts in the area of ​​peripheral nerve endings, causing their reversible blocking. It has a quick and long-lasting local anesthetic effect. After applying the paste to the oral mucosa, the pain stops within 2-5 minutes; pain relief lasts for 3-5 hours.

Solcoseryl dental adhesive paste forms a protective healing layer on the affected area of ​​the oral mucosa and protects it from mechanical and chemical damage for 3-5 hours, performing the function of a medicinal bandage.

Solcoseryl dental adhesive paste 5g

Description

Light beige, granular, easily distributed homogeneous mass with the smell of peppermint.

Release form

5 g in aluminum tubes. The tube, along with instructions for use, is placed in a cardboard box.

special instructions

You should not put Solcoseryl dental adhesive paste into the wound cavity formed as a result of the removal of molars, wisdom teeth, as well as apicotomy (resection of the apex of the tooth), if the edges of the tooth socket are tightened with subsequent sutures. Solcoseryl dental adhesive paste does not contain anti-infective components. In case of acute infection of the affected area of ​​the oral mucosa, which is subject to treatment with this drug, it is necessary to carry out preliminary medical treatment/treatment of the affected area aimed at eliminating the symptoms of inflammation.

pharmachologic effect

Solcoseryl is a deproteinized hemodialysate that contains a significant amount of low-molecular components of cells and blood serum of calves (dialysis/ultrafiltration, maximum molecular weight 5000 Da), the chemical and pharmacological properties of which are only partially described to date. A study of the drug on various cell and tissue cultures, organs, as well as animals showed that Solcoseryl: maintains and/or restores aerobic energy metabolism, as well as oxidative phosphorylation processes in cells deprived of sufficient nutrients, thereby maintaining and/or restoring supply of high-energy phosphates, increases oxygen uptake (in vitro), as well as glucose transport in hypoxic and metabolically depleted tissues and cells, improves repair and regeneration processes in damaged tissues and/or tissues deprived of sufficient nutrients, prevents and/or reduces secondary degeneration and pathological changes in reversibly damaged cellular systems, enhances collagen synthesis in in vitro models, and also stimulates cell proliferation and migration in vitro. Consequently, Solcoseryl dental adhesive paste protects tissues prone to hypoxia and/or substrate depletion. It stimulates the restoration of functions in reversibly damaged tissue, and also accelerates the healing of lesions and improves the quality of this process. Macrogol-9-lauryl ether (Polidocanol 600), a topical anesthetic, reversibly blocks peripheral nerve endings. Due to its high wetting ability, the analgesic effect occurs within 1-3 minutes after application. Due to the adhesive ability of the paste, this effect can last from 1 to 5 hours, depending on the location of the lesion and salivation. After swelling under the influence of saliva and wound secretions, the paste base, consisting of pectin, gelatin, sodium carboxymethylcellulose, liquid paraffin and polyethylene, forms an adhesive and elastic protective film on the wound.

Indications for use

Solcoseryl dental adhesive paste is used for local acceleration of healing, pain relief and protection of the wound surface in the following diseases and conditions: Treatment of painful and inflammatory processes of the oral mucosa, gums and lips (aphthae, labial herpes, gingivitis, periodontitis, stomatitis) Treatment of lesions caused by pressure of dentures on tissue (bedsores) Treatment of complications associated with the appearance of wisdom teeth Treatment of wounds after removal of tartar, curettage, periodontal surgery, tooth extraction and installation of immediate dentures Alveolitis.

Directions for use and doses

The drug is intended for local use in the oral mucosa. The affected surface of the mucous membrane must first be dried with a cotton or gauze swab. Apply a strip of paste about 0.5 cm long, without rubbing, onto the mucous membrane in a thin layer using a finger or a cotton swab, and then lightly moisten the applied paste with water. The procedure is repeated 3-5 times a day after meals and before bedtime. Treatment is carried out until symptoms disappear. Solcoseryl dental adhesive paste forms a protective healing layer on the affected area of ​​the oral mucosa and protects it from mechanical and chemical damage for 3-5 hours. When applying the paste to undried mucous membranes, the duration of the therapeutic effect may be reduced. When treating bedsores from removable dentures, apply the paste to a dry denture and moisten with water. The recommended course dose of the drug is 1 tube (5 g). Special categories of patients Children The effectiveness and safety of the drug in children aged 2-5 years have not been sufficiently studied. There are no restrictions regarding the use of the drug in children over 2 years of age. There are no restrictions regarding the use of the drug in elderly patients.

Use during pregnancy and lactation

Animal studies have shown no risk to the fetus, but there have been no controlled studies in pregnant women. Caution should be exercised when used during pregnancy. There are no objections to the use of Solcoseryl dental adhesive paste during lactation.

Interaction with other drugs

To date, there have been no cases of interaction between Solcoseryl dental adhesive paste and other drugs. When simultaneously prescribing Solcoseryl dental adhesive paste and other drugs in the form of rinses, the paste should be applied after using these drugs.

Contraindications

individual sensitivity to any of the components of the drug (to preservatives - esters of parahydroxybenzoic acid (E216 and E218)), including free parahydroxybenzoic acid (E 210), the presence of a residual amount of which is due to the peculiarities of the technological process during the production of the drug. Infants and children under two years of age: Peppermint oil and levomenthol may cause spasm of the larynx, leading to serious breathing problems.

Compound

per 1 g Active ingredients: Solcoseryl (deproteinized dialysate from the blood of dairy calves), in terms of dry matter - 2.125 mg; polidocanol - 10,000 mg. Excipients: sodium carboxymethylcellulose, methyl parahydroxybenzoate (E 218), propyl parahydroxybenzoate (E 216), peppermint oil, menthol. Paste base: sodium carboxymethylcellulose, gelatin, pectin, polyethylene, liquid paraffin.

Overdose

There is no information on the effects of an overdose of the drug.

Side effect

change in taste sensations: allergic reactions (local swelling) are possible, if they occur, you must stop using the drug and consult a doctor. In rare cases (less than 0.01%), allergic reactions, in particular shortness of breath, may develop. In such cases, you should stop using the drug. May cause laryngospasm in infants and children under 2 years of age.

Storage conditions

Store at a temperature not exceeding 25°C. Keep out of the reach of children! The granular-dry consistency of the paste ensures its optimal adhesive properties and is not a sign of deterioration in the quality of the drug. When opening the tube, oil may be released, which is also not a sign of deterioration in the quality of the drug.

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Instructions for use for Solcoseryl dental adhesive paste 5g

Directions for use and dosage

The drug is intended for local use on the oral mucosa.

The affected surface of the mucous membrane must first be dried with a cotton or gauze swab. Apply a strip of paste about 0.5 cm long, without rubbing, onto the mucous membrane in a thin layer with your finger or using a cotton swab, and then lightly moisten the applied paste with water. The procedure is repeated 3-5 times a day after meals and before bedtime. Treatment is carried out until symptoms disappear.

Solcoseryl dental adhesive paste forms a protective therapeutic layer on the affected area of ​​the oral mucosa and protects it from mechanical and chemical damage for 3-5 hours. When applying the paste to undried mucosa, the duration of the therapeutic effect can be reduced.

When treating bedsores from removable dentures, apply the paste to a dry denture and moisten with water.

The recommended course dose of the drug is 1 tube (5 g).

Gel Solcoseryl: reviews

An important condition for achieving a good treatment result is the correct choice of the form of the drug Solcoseryl - this can be in the form of a gel, ointment or dental adhesive paste.
The effect of the gel will be noticeable specifically on wet wounds, and consists in accelerating the formation of granulation tissue by about 30%. You will not notice the effect of the gel when used on dry wounds, and it is unlikely that you will be able to leave a good review of the product after this. Solcoseryl gel will have a good pronounced effect and will accelerate the healing of wounds and ulcer erosions, unless, of course, they are related to tumor-like lesions. The latter must be especially borne in mind, because if the erosion or ulcer has existed for a long time, or there is no effect when using Solcoseryl, then these are signals indicating that this lesion of the mucous membrane/skin is related to tumor-like tissue damage.

Another important point is applying the drug to infected wounds. For the drug to give a good result, there must be no infection in the wound. Purulent wounds, as well as wounds with torn edges, first require primary surgical treatment and drug therapy. Reviews for Solcoseryl gel will be positive only if you carefully follow all recommendations for its use. Failure to follow the recommendations for use, especially with regard to infected wounds, can, on the contrary, lead to increased inflammation.

Solcoseryl anti-wrinkle gel in cosmetology: reviews

Some patients persistently try to use Solcoseryl gel for the face to get rid of wrinkles. The logic here is clear - since the drug increases proliferation (reproduction) and activity of fibroblasts, then its use should seem to lead to an increase in collagen production. Unfortunately for patients, it must be noted that none of the forms of solcoseryl work on intact skin.

Therefore, Solcoseryl ointment or gel is not used in cosmetology, and they are effective only for accelerating the healing of skin damage, including after surgical and cosmetic interventions. To stimulate collagen production in aging skin, it is better to use retinoid-based products, and an even faster effect is achieved by a hardware technique that uses fractional lasers. These techniques do have proven evidence of increasing collagen in the skin (see links above for arguments and clinical studies).

If you are interested in a cream that can improve skin regeneration and keep it moisturized, especially in winter, one of the best options would be to use Bepanthen for Dry Skin cream. It contains not only dexpanthenol (a precursor to vitamin B5, which enhances skin regeneration), but also moisturizing components such as the emollient “lanolin”, as well as D, L-pantolactone. I recommend this product because... I myself use it 2 times a day in the winter and see its effectiveness from personal experience. It can even be applied to the moving parts of the eyelids. A 100 ml tube costs only about 950 rubles.

Nosological classification (ICD-10)

• K05.0 Acute gingivitis
• K05.1 Chronic gingivitis
• K05.3 Chronic periodontitis
• K05.6 Periodontal disease, unspecified
• K06 Other changes in the gingiva and edentulous alveolar margin
• K12 Stomatitis and related lesions
• K12.0 Recurrent oral aphthae
• K13.0 Diseases of the lips
• K13.7 Other and unspecified lesions of the oral mucosa
• Z96.5 Presence of dental and jaw root implants
• Z97.2 Presence of dental prosthetic device (complete) (partial)

Composition and release form

in tubes of 5 g; 1 tube in a box.

special instructions

You should not put Solcoseryl dental adhesive paste into the wound cavity formed as a result of the removal of molars, wisdom teeth, as well as apicotomy (resection of the apex of the tooth), if the edges of the tooth socket are tightened with subsequent sutures.

Solcoseryl dental adhesive paste does not contain anti-infective components. In case of acute infection of the affected area of ​​the oral mucosa, which is subject to treatment with this drug, it is necessary to carry out preliminary medical treatment/treatment of the affected area aimed at eliminating the symptoms of inflammation.