Toothache always brings unpleasant sensations that cause severe discomfort. Moreover, it can arise at a completely unexpected moment. In order to muffle these sensations, you have to take analgesics. One of these is the toothache remedy Tempalgin. It should be used when pain occurs, which may be accompanied by an inflammatory process. But before using this drug, you should carefully read the instructions for use.
Characteristic
Tempalgin is a pain reliever that is often used to dull the sensation of toothache.
Tempalgin can only slightly dull toothache
This remedy is often available in pharmacies without a prescription. Over-the-counter availability is explained by the fact that this drug, compared to other prescription painkillers, has a rather low effectiveness.
It is worth noting that Tempalgin cannot always save you from toothache; in addition, it is often ineffective, especially with severe pain.
In its properties and composition, this remedy is similar to the well-known drug Analgin. It can also relieve mild pain, but in case of acute discomfort due to pulpitis and periodontitis, it only slightly weakens them.
Components
The main effect of the drug Tempalgin is ensured due to its composition. The medicine contains the following components:
- Metamizole sodium
- Triacetonamine-4-toluenesulfonate or tempidone
- Additional components
The product is produced in the form of round tablets. The top of the tablets is covered with a film coating, which is green in color; a cross section shows a white color.
The tablets are placed in blisters made of aluminum material. Each blister contains 10 tablets. The cardboard packaging contains 2 or 10 blisters.
pharmachologic effect
Tampalgin has analgesic, antipyretic, anti-inflammatory, and sedative effects.
The analgesic and anti-inflammatory effect is provided due to the ability of the active component metemizole sodium to block the process of the appearance of prostaglandin components, which are responsible for inflammation in the human body.
The principle of action of this drug is based on reducing pain. But at the same time, the active components of the drug have a low anti-inflammatory effect.
Tempidone, which is part of tempalgin, has a calming effect on the nervous system
The second active component, tempidon, penetrates the circulatory system and has a calming effect. In this case, the nervous system is under the influence of a pronounced sedative, calming effect.
The combination of methimizole sodium and tempidone helps to increase the analgesic effect of the former, and also increases the period of action of the drug.
After administration, the effect of the drug Tempalgin occurs within half an hour. The period of action is from 1 hour and can last up to two hours.
The drug is excreted by the kidneys along with urine. Excreted in the form of metabolites. The bioavailability level is about 90%. Eating food does not affect pharmacokinetics.
Effect of the drug on toothache
When using Tempalgin for tooth pain, it is worth considering that this remedy can act in different ways. Therefore, it is worth paying attention to the features of this remedy:
- Tempalgin cannot always eliminate the strong pulsating pain that occurs with pulpitis and periodontitis. He just weakens the intensity of these sensations a little
- The effect of the drug is similar to Analgin. Therefore, it should be used only for weak, aching painful feelings.
- Since the medicine has a weak anti-inflammatory effect, its use for tumors of the gums, cheeks, as well as inflammation of the area located next to the affected tooth may be ineffective
- Tempalgin can have different effects on everyone. For some, this remedy can help get rid of severe pain, but for others, on the contrary, even after taking several tablets it will not help reduce even mild pain.
Comparison of the safety of Ibuprofen and Tempalgin
The safety of a drug includes many factors.
At the same time, it is higher for Ibuprofen than for Tempalgin. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Ibuprofen, as well as Tempalgin, we look at which organ is the metabolizing organ and how critical the effect on it is.
The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Ibuprofen has fewer risks when used than Tempalgin.
Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Ibuprofen and Tempalgin.
How to apply
According to the instructions, the medicine is taken orally. It can be taken with or after food.
Features of application:
- One tablet is taken at a time
- The patient can control the number of appointments himself. Typically, the number of doses depends on the intensity of the pain, its duration, and the effectiveness of the medicine on the patient. There can be a maximum of three doses per day
- The tablets are round in shape and large in size, but despite this, taking them does not cause any particular difficulties. Due to the fact that they have an even, smooth coating, they can be easily swallowed, but it is advisable to wash them down with enough water.
- If the pain does not go away or its intensity does not decrease, then in these cases you can increase the dosage or number of doses. It is allowed to take two tablets at a time, but if you save the number of doses - three times, 2 tablets. You can also increase the number of doses up to 4 times, for example, one tablet in the morning, two tablets at lunch and evening, and one tablet before bedtime
Comparison of addiction between Ibuprofen and Tempalgin
Like safety, addiction also involves many factors that must be considered when evaluating a drug.
So, the totality of the values of such parameters as “o syndrome” in Ibuprofen is quite similar to the similar values in Tempalgin. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, Ibuprofen has a fairly low incidence of “syndrome”, just like Tempalgin.
What contraindications does the drug have?
During use, it is worth considering that there are indications for which taking Tempalgin is not recommended.
Arterial hypotension is one of the contraindications to the use of Tempalgin
Contraindications for use include the following conditions:
- Presence of severe liver failure
- In acute liver failure
- Should not be used in chronic heart failure
- During arterial hypotension (this condition is characterized by the presence of a systolic blood pressure level below 100 mmHg)
- When hematopoiesis is suppressed - granulocytopenia, leukopenia, agranulocytosis, as well as neutropenia in cytostatic and infectious forms
- If you have alcohol addiction
- Should not be used by women during pregnancy
- When breastfeeding
- Children under 14 years old
Why is it not recommended to use during pregnancy and breastfeeding?
Important! Tempalgin should not be used during pregnancy, especially in the first trimester and in the last 6 weeks. The constituent components can have a harmful effect on the child and can also cause developmental pathologies.
During other periods of pregnancy, it is recommended to use the medicine only strictly according to indications and under the constant supervision of the attending physician. It is advisable to use only when absolutely necessary.
Tempalgin is prohibited when breastfeeding. The constituent components are excreted together with breast milk.
Comparison of ease of use of Ibuprofen and Tempalgin
This includes dose selection taking into account various conditions and frequency of doses. At the same time, it is important not to forget about the release form of the drug; it is also important to take it into account when making an assessment.
The ease of use of Ibuprofen is approximately the same as Tempalgin. However, they are not convenient enough to use.
The drug ratings were compiled by experienced pharmacists who studied international research. The report is generated automatically.
Last update date: 2020-12-04 13:44:51
Side effects
Side effects are rare; usually their occurrence is due to non-compliance with the rules of administration. If you use the medicine in increased dosages, unwanted side effects associated with the nervous, digestive or circulatory system may appear. Sometimes various allergic reactions may occur.
Common side effects include the following conditions:
- Frequent dizziness, headaches
- The appearance of pain in the epigastric area
- Dry mouth
- Disorders of the nervous system may appear - hallucinations, sleep disturbances
- Decreased or increased blood pressure
- Jaundice
- Tachycardia condition
- The use of the drug may cause a decrease in the level of leukocytes in the blood, which may result in leukopenia.
- Sometimes thrombocytopenia, agranulocytosis occurs
- Urine may turn red
- Feeling itchy
- The occurrence of impaired functioning of the kidneys and liver
- Various allergic reactions
Comparison of side effects of Ibuprofen and Tempalgin
Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.
Ibuprofen has almost the same side effects as Tempalgin. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Ibuprofen are similar to Tempalgin: how quickly the body recovers after taking it and whether it recovers at all.
Analogs
The closest analogue of Tempalgin is Aspirin, other drugs are more effective but can be purchased with a prescription
The common well-known drug Aspirin has a similar effect to Tempalgin. It is also mildly potent, so it can be used for minor pain and inflammation. But since, unlike Tempalgin, Aspirin has a different active ingredient, it can be effective in cases where the use of Tempalgin does not give much effect.
In addition to Aspirin, you can replace Tempalgin with other over-the-counter medications:
- Nurofen
- Ibuprofen
- Buran
The following painkillers for toothache have a stronger effect:
- Nimesil in powder form
- Ketones
- Ketorol
- Ketanal
- Ketorolac
But these drugs are available from pharmacies only with a doctor's prescription.
But still, you should not use painkillers to treat toothache. In any case, its occurrence will serve as a signal about the emergence of an unhealthy process in the tooth.
Tempalgin and other painkillers can only be used as first aid, but not as the main treatment.
Comparison of the effectiveness of Ibuprofen and Tempalgin
Tempalgin is more effective than Ibuprofen - this means that the ability of the drug to provide the maximum possible effect is different.
For example, if the therapeutic effect of Tempalgin is more pronounced, then it is impossible to achieve this effect with Ibuprofen, even in large doses.
Also, the speed of therapy is an indicator of the speed of the therapeutic action; Tempalgin and Ibuprofen are also different, as is bioavailability - the amount of a drug reaching the site of its action in the body. The higher the bioavailability, the less it will be lost during absorption and use by the body.
